學歷

• 臺北醫學大學醫學院醫學士

經歷

• 臺北醫學大學附設醫院婦產部產科主任

• 臺北醫學大學醫學院專任助理教授

• 台灣周產期醫學會理事

• 母嬰親善醫療院所認證委員

• 國際認證泌乳顧問

專科證照

• 中華民國婦產科專科醫師

• 中華民國周產期專科醫師

• 中華民國婦產科超音波專業醫師

• 高危險妊娠照護

獎項與榮耀

1. 97 年 商業周刊 醫生推薦的六百良醫
2. 102年 台北醫學大學附設醫院 最佳主治醫師
3. 103年 台北醫學大學醫學系 最佳主治醫師
4. 103年 台北醫學大學附設醫院 最佳主治醫師
5. 103年 台北醫學大學附設醫院 優良教師優良教學獎
6. 105年 台北醫學大學附設醫院 資深優良教師獎
7. 108年 台北醫學大學醫學系 最佳主治醫師

期刊論文

1. Chien LW, Au HK, Sheen TC, Tzeng CR. Cogwheel sign of hydrosalpinx. New Taipei Journal of Medicine 2000;2:224
2. Sheen TC, Chen SR, Au HK, Chien YY, Wu KY, Tzeng CR. Herniated blastomere following chemically assisted hatching may result in monozygotic twins. Fertility & Sterility 2001;75:442-444
3. Tsui K, Chang CW, Au HK, Chien YY, Chien LW, Tzeng CR. Fertility trends in mainland China,1970-2000. New Taipei Journal of Medicine 2001;3:149-160
4. Tai CJ, Au HK, Chang CW, Tzeng CR. Prediction of preterm labor by fetal fibronectin. New Taipei Journal of Medicine 2002;4:51-56
5. Chien LW, Au HK, Xiao J, Tzeng CR. Fluid accumulation within the uterine cavity reduces pregnancy rates in women undergoing IVF. Human Reproduction 2002 ;17:351-356.
6. Hsieh RH, Tsai NM, Au HK, Chang SJ, Wei YH, Tzeng CR.Multiple rearrangements of mitochondrial DNA in unfertilized human oocytes. Fertility & Sterility 2002 ;77:1012-1017.
7. Chien LW, Au HK, Chen PL, Xiao J, Tzeng CR.Assessment of uterine receptivity by the endometrial-subendometrial blood flow distribution pattern in women undergoing in vitro fertilization-embryo transfer. Fertility & Sterility 2002 ;78:245-251.
8. Chao JC, Tseng HP, Chang CW, Chien YY, Au HK, Chen JR, Chen CF. Chicken extract affects colostrum protein compositions in lactating women. Journal of Nutritional Biochemistry 2004 ;15:37-44.
9. Hsieh RH, Au HK, Yeh TS, Chang SJ, Cheng YF, Tzeng CR.Decreased expression of mitochondrial genes in human unfertilized oocytes and arrested embryos. Fertility & Sterility 2004 ;81:912-918.
10. Chien LW, Lee WS, Au HK, Tzeng CR.Assessment of changes in utero-ovarian arterial impedance during the peri-implantation period by Doppler sonography in women undergoing assisted reproduction. Ultrasound in Obstetrics Gynecology 2004 ;23:496-500.
11. Yang WC, Chen HW, Au HK, Chang CW, Huang CT, Yen YH, Tzeng CR. Serum and endometrial markers. Best Practice Research Clinical Obstetrics Gynaecology 2004 ;18:305-318.
12. Chen HW, Chen JJ, Yu SL, Li HN, Yang PC, Su CM, Au HK, Chang CW, Chien LW, Chen CS, Tzeng CR. Transcriptome analysis in blastocyst hatching by cDNA microarray. Hum Reprod. 2005;20(9):2492-501.
13. Yang WC, Au HK, Chang CW, Chen HW, Chen PH, Chen CC, Tang YL, Wang IT, Tzeng CR. Matrix remodeling and endometriosis. Reproductive Medicine and Biology 2005;4:93-99
14. Au HK, Yeh TS, Kao SH, Tzeng CR, Hsieh RH. Abnormal mitochondrial structure in human unfertilized oocytes and arrested embryos. Annals of the New York Academy of Sciences 2005;1042:177-85.
15. Au HK, Lin SH, Huang SY, Yeh TS, Tzeng CR, Hsieh RH. Deleted mitochondrial DNA in human luteinized granulosa cells. Annals of the New York Academy of Sciences 2005;1042:136-41
16. Tsai NM, Hsieh RH, Au HK, Shieh MJ, Huang SY, Tzeng CR. Effects of gonadotrophin-releasing hormone agonists on apoptosis of granulosa cells. Annals of the New York Academy of Sciences. 2005;1042:531-7
17. Au HK, Yeh TS, Kao SH, Shih CM, Hsieh RH, Tzeng CR. Calcium-dependent up-regulation of mitochondrial electron transfer chain gene expressions in human luteinized granulosa cells. Fertility & Sterility. 2005; 84:Suppl 2:1104-8
18. Huang CT, AU HK, Chien LW, Chang CW, Chien YY, *Tzeng CR. Twin pregnancy outcome among cases of spontaneous conception, intrauterine insemination, and in vitro fertilization/intracytoplasmic sperm injection. Fertility & Sterility 2006; 86(4):1017-9
19. Leung TK, AU HK, Lin YH, Lee CM, Shen LK, Lee WH, Wang HJ, Hsiao WT, *Chen YY. Prophylactic trans-uterine embolization to reduce intraoperative blood loss for placenta percreta invading the urinary bladder. J. Obstet. Gynecol. Res. 2007; 33(5):722-725
20. Chien LW, Liu WM, Tzeng CR, *Au HK. Effect of previous live birth and prior route of delivery on the outcome of early medical abortion. Obstet Gynecol. 2009 Mar;113(3):669-74
21. Wang LM, Wang PH, Chen CL, Au HK, Yen YK, *Liu WM. Uterine preservation in a woman with spontaneous uterine rupture secondary to placenta percreta on the posterior wall: a case report. J Obstet Gynecol Res. 2009 Apr;35(2):379-84.Review
22. Yang RB*, Au HK* (*equal contribution), Tzeng CR, Tsai MT, Wu P, Wu YC, Ling TY, Huang YH. Characterization of a novel cell-surface protein expressed on human sperm. Hum Reprod. 2010 Jan;25(1):42-51.;
23. Juan YC, Au HK, Hsu JJ, Ma PC, Liu WM, *Jeng CJ. Bell palsy and preeclampsia superimposed on chronic hypertension. Taiwan J Obstet Gynecol. 2010 Jun;49(2):223-4
24. Lu SH, Yen YK, Ling TY, Cheng KT, Shu JA, Au HK, *Huang YH Capacitation suppression by mouse seminal vesicle autoantigen involves a decrease in plasma membrane Ca2+-ATPase (PMCA)-mediated intracellular calcium. J Cell Biochem. 2010 Dec 1;111(5):1188-98.
25. Chen CP, Lin YH, Au HK, Su YN, Hsu CY, Liu YP, Wu PC, Chern SR, Chen YT, Chen LF, Hsieh AH, Wang W. Chromosome 15q overgrowth syndrome: prenatal diagnosis, molecular cytogenetic characterization, and perinatal findings in a fetus with dup(15)(q26.2q26.3). Taiwan J Obstet Gynecol. 2011 Sep;50(3):359-65.
26. Chen CM, Li SC, Chen CY, Au HK, Shih CK, Hsu CY, Liu JF. Constituents in purple sweet potato leaves inhibit in vitro angiogenesis with opposite effects ex vivo. Nutrition. 2011 Nov-Dec;27(11-12):1177-82
27. Liao CJ, Huang YH, Au HK, Wang LM, Chu ST. The cancer marker neutrophil gelatinase-associated lipocalin is highly expressed in human endometrial hyperplasia. Mol Biol Rep. 2012 Feb;39(2):1029-36
28. Huang CY, Lin FY, Shih CM, Au HK, Chang YJ, Nakagami H, Morishita R, Chang NC, Shyu KG, Chen JW. Moderate to high concentrations of high-density lipoprotein from healthy subjects paradoxically impair human endothelial progenitor cells and related angiogenesis by activating rho-associated kinase pathways. Arterioscler Thromb Vasc Biol. 2012 Oct;32(10):2405-17
29. Tzeng CR*, Hwang JL* (*equal contribution), Au HK, Chien LW. Sonographic patterns of the endometrium in assessment of medical abortion outcomes. Contraception. Contraception. 2013 Jul;88(1):153-9
30. Chang JH*, Au HK*(*equal contribution) , Lee WC, Chi CC, Ling TY, Wang LM, Kao SH, Huang YH, Tzeng CR. Expression of the pluripotent transcription factor OCT4 promotes cell migration in endometriosis. Fertil Steril. 2013;99:1332-9.
31. Lu YY, Su ML, Gau ML, Lin KC, Au HK The efficacy of cold-gel packing for relieving episiotomy pain - a quasi-randomised control trial. Contemp Nurse 2015 Feb;50(1):26-35. doi: 10.1080/10376178.2015.1010257.
32. Au HK, Chang JH, Wu YC, Kuo YC, Chen YH, Lee WC, Chang TS, Lan PC, Kuo HC, Lee KL, Lee MT, Tzeng CR, Huang YH. TGF-βI Regulates Cell Migration through Pluripotent Transcription Factor OCT4 in Endometriosis. PLoS One 2015 Dec 16;10(12):e0145256. doi: 10.1371/journal.pone.0145256.
33. Alibekova R, Huang JP, Lee TS, Au HK, Chen YH. Effects of smoking on perinatal depression and anxiety in mothers and fathers: A prospective cohort study. J Affect Disord. 2016 Mar 15;193:18-26. doi: 10.1016/j.jad.2015.12.027.
34. Au HK, Liu CF, Tzeng CR, Chien LW. Association between ultrasonographic parameters of cesarean scar defect and outcome of early termination of pregnancy. Ultrasound Obstet Gynecol. 2016 Apr,47(4)506-10. doi:10.1002/uog.14877.
35. Kuo YC*, Au HK*(*equal contribution), Hsu JL, Wang HF, Lee CJ, Peng SW, Lai SC, Wu YC, Ho HN, Huang YH. IGF-1R promotes symmetric self-renewal and migration of alkaline phosphatase⁺ germ stem cells through HIF-2a-OCT4/CXCR4 loop under hypoxia. Stem Cell Reports. 2018 Feb 13;10:524-37. doi.org/10.1016/j.stemcr.2017.12.003
36. Lin YH, Chen YH, Chang HY, Au HK, Tzeng CR, Huang YH. Chronic niche inflammation in endometriosis-associated infertility: Current understanding and future therapeutic strategies. Int J Mol Sci. 2018 Aug 13;19(8). pii: E2385. doi: 10.3390/ijms19082385. Review.PMID:30104541
37. Chen YH, Huang JP, Au HK, Chen YH. High risk of depression, anxiety, and poor quality of life among experienced fathers, but not mothers: A prospective longitudinal study. J Affect Disord. 2019 Jan 1;242:39-47. doi: 10.1016/j.jad.2018.08.042. Epub 2018 Aug 11.
38. Wang HY, Huang JP, Lin CL, Au HK, Chen YH. Paternal influences from early pregnancy to postpartum years on child development: A longitudinal study. J Affect Disord. 2020 Oct 1;275:23-30. doi: 10.1016/j.jad.2020.06.018. Epub 2020 June 24. PMID:32658819
39. Tseng JF, Chen SR, Au HK, Chipojola R, Lee GT, Lee PH, Shyu Ml, Kuo SY. Effectiveness of an integrated breastfeeding education to improve self-efficacy and exclusive breastfeeding rate: A single-blind, randomized controlled study. Int J Nurs Stud. 2020 Nov;111:103770. doi: 10.1016/j.ijnurstu.2020.103770. Epub 2020 Sep 3. PMID:32961461
40. Au HK*(*equal contribution), Peng SW*, Guo CL*, Lin CC, Wang YL, Kuo YC, Law TY, Ho HN, Ling TY, Huang YH. Niche laminin and IGF-1 additively coordinate the maintenance of Oct-4 through CD49f/IGF-1R-Hif-2a feedforward loop in mouse germline stem cells. Front Cell Dev Biol. 2021 Jul 26;9:646644. doi: 10.3389/fcell.2021.646644. eCollection 2021.PMID: 34381769 
41. Wang CW, Chang TH, Chuang NC, Au HK, Chen CH, Tseng SH. Association between intracytoplasmic sperm injection and neurodevelopmental outcomes among offspring. PLoS One. 2021 Sep 10;16(9):e0257268. doi: 10.1371/journal.pone.0257268. eCollection 2021.PMID: 34506583

專書論文

1. Hsieh RH, Au HK, Wang RS, Yang PS, Tzeng CR. The role of mitochondria in the aging ovary. The ovary. Elsevier 2004:569-575
2. Chien LW, Au HK. Interventions for failed family planning. Family planning. IntechOpen 2018:170-182
3. Lin YH, Chen YH, Chang HY Chang, Au HK , Tzeng CR, Huang YH. Chronic niche inflammation in endometriosis-associated infertility: Current understanding and future therapeutic strategies. Molecular research of endometrial pathophysiology. MDPI 2019:133-165

研討會論文

• Role of targeted fetal ultrasound examination in combination of chromosome microarray analysis for prenatal diagnosis. Best Oral Award  Present in the 16^th World Federation for Ultrasound in Medicine and Biology Congress in 2017 (WFUMB 2017 Taipei).